Using lysine adducts of human serum albumin to investigate the disposition of exogenous formaldehyde in human blood

Formaldehyde is a human carcinogen that readily binds to nucleophiles, including proteins and DNA. To investigate whether exogenous formaldehyde produces adducts in extracellular fluids, we characterized modifications to human serum albumin (HSA) following incubation of whole blood, plasma, and sali...

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Detalhes bibliográficos
Publicado no:Toxicol Lett
Main Authors: Regazzoni, Luca G., Grigoryan, Hasmik, Ji, Zhiying, Chen, Xi, Daniels, Sarah I., Huang, Deyin, Sanchez, Sylvia, Tang, Naijun, Sillé, Fenna C. M., Iavarone, Anthony T., Williams, Evan R., Zhang, Luoping, Rappaport, Stephen M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5555303/
https://ncbi.nlm.nih.gov/pubmed/28104429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.toxlet.2017.01.002
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