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Arginine methylation regulates c-Myc–dependent transcription by altering promoter recruitment of the acetyltransferase p300

Protein arginine methyltransferase 1 (PRMT1) is an essential enzyme controlling about 85% of the total cellular arginine methylation in proteins. We have shown previously that PRMT1 is an important regulator of innate immune responses and that it is required for M2 macrophage differentiation. c-Myc...

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Detalles Bibliográficos
Publicado en:J Biol Chem
Main Authors: Tikhanovich, Irina, Zhao, Jie, Bridges, Brian, Kumer, Sean, Roberts, Ben, Weinman, Steven A.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5555193/
https://ncbi.nlm.nih.gov/pubmed/28652407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.797928
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