Serine 574 phosphorylation alters transcriptional programming of FOXO3 by selectively enhancing apoptotic gene expression

Forkhead box O3 (FOXO3) is a multispecific transcription factor that is responsible for multiple and conflicting transcriptional programs such as cell survival and apoptosis. The protein is heavily post-translationally modified and there is considerable evidence that post-transcriptional modificatio...

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Bibliografiske detaljer
Udgivet i:Cell Death Differ
Main Authors: Li, Z, Zhao, J, Tikhanovich, I, Kuravi, S, Helzberg, J, Dorko, K, Roberts, B, Kumer, S, Weinman, S A
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2016
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Original Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4986632/
https://ncbi.nlm.nih.gov/pubmed/26470730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2015.125
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