Bromodomain and extraterminal inhibitors block the Epstein-Barr virus lytic cycle at two distinct steps

Lytic infection by the Epstein-Barr virus (EBV) poses numerous health risks, such as infectious mononucleosis and lymphoproliferative disorder. Proteins in the bromodomain and extraterminal (BET) family regulate multiple stages of viral life cycles and provide promising intervention targets. Synthet...

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Dades bibliogràfiques
Publicat a:J Biol Chem
Autors principals: Keck, Kristin M., Moquin, Stephanie A., He, Amanda, Fernandez, Samantha G., Somberg, Jessica J., Liu, Stephanie M., Martinez, Delsy M., Miranda, JJ L.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2017
Matèries:
Microbiology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5555189/
https://ncbi.nlm.nih.gov/pubmed/28588024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.751644
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