Bromodomain and extraterminal inhibitors block the Epstein-Barr virus lytic cycle at two distinct steps

Lytic infection by the Epstein-Barr virus (EBV) poses numerous health risks, such as infectious mononucleosis and lymphoproliferative disorder. Proteins in the bromodomain and extraterminal (BET) family regulate multiple stages of viral life cycles and provide promising intervention targets. Synthet...

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Bibliografiske detaljer
Udgivet i:J Biol Chem
Main Authors: Keck, Kristin M., Moquin, Stephanie A., He, Amanda, Fernandez, Samantha G., Somberg, Jessica J., Liu, Stephanie M., Martinez, Delsy M., Miranda, JJ L.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2017
Fag:
Microbiology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5555189/
https://ncbi.nlm.nih.gov/pubmed/28588024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.751644
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