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Enantioselective Construction of Acyclic Quaternary Carbon Stereocenters: Palladium-Catalyzed Decarboxylative Allylic Alkylation of Fully-Substituted Amide Enolates

We report a divergent and modular protocol for the preparation of acyclic molecular frameworks containing newly created quaternary carbon stereocenters. Central to this approach is a sequence composed of a (1) regioselective and -retentive preparation of allyloxycarbonyltrapped fully-substituted ste...

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Библиографические подробности
Опубликовано в: :J Am Chem Soc
Главные авторы: Starkov, Pavel, Moore, Jared T., Duquette, Douglas C., Stoltz, Brian M., Marek, Ilan
Формат: Artigo
Язык:Inglês
Опубликовано: 2017
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5555155/
https://ncbi.nlm.nih.gov/pubmed/28625056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.7b04086
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