Peptide methionine sulfoxide reductase from Escherichia coli and Mycobacterium tuberculosis protects bacteria against oxidative damage from reactive nitrogen intermediates

Inducible nitric oxide synthase (iNOS) plays an important role in host defense. Macrophages expressing iNOS release the reactive nitrogen intermediates (RNI) nitrite and S-nitrosoglutathione (GSNO), which are bactericidal in vitro at a pH characteristic of the phagosome of activated macrophages. We...

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Detalhes bibliográficos
Main Authors: John, Gregory St., Brot, Nathan, Ruan, Jia, Erdjument-Bromage, Hediye, Tempst, Paul, Weissbach, Herbert, Nathan, Carl
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2001
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC55550/
https://ncbi.nlm.nih.gov/pubmed/11481433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.161295398
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