Peptide methionine sulfoxide reductase from Escherichia coli and Mycobacterium tuberculosis protects bacteria against oxidative damage from reactive nitrogen intermediates

Inducible nitric oxide synthase (iNOS) plays an important role in host defense. Macrophages expressing iNOS release the reactive nitrogen intermediates (RNI) nitrite and S-nitrosoglutathione (GSNO), which are bactericidal in vitro at a pH characteristic of the phagosome of activated macrophages. We...

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Détails bibliographiques
Auteurs principaux: John, Gregory St., Brot, Nathan, Ruan, Jia, Erdjument-Bromage, Hediye, Tempst, Paul, Weissbach, Herbert, Nathan, Carl
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2001
Sujets:
Biological Sciences
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC55550/
https://ncbi.nlm.nih.gov/pubmed/11481433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.161295398
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