A survey of homozygous deletions in human cancer genomes

Homozygous deletions of recessive cancer genes and fragile sites are known to occur in human cancers. We identified 281 homozygous deletions in 636 cancer cell lines. Of these deletions, 86 were homozygous deletions of known recessive cancer genes, 17 were of sequenced common fragile sites, and 178...

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Main Authors: Cox, Charles, Bignell, Graham, Greenman, Chris, Stabenau, Arne, Warren, William, Stephens, Philip, Davies, Helen, Watt, Stephen, Teague, Jon, Edkins, Sara, Birney, Ewan, Easton, Douglas F., Wooster, Richard, Futreal, P. Andrew, Stratton, Michael R.
格式: Artigo
語言:Inglês
出版: National Academy of Sciences 2005
主題:
Biological Sciences
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC555487/
https://ncbi.nlm.nih.gov/pubmed/15761058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0408593102
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