Single-Cell Landscape of Transcriptional Heterogeneity and Cell Fate Decisions during Mouse Early Gastrulation

The mouse inner cell mass (ICM) segregates into the epiblast and primitive endoderm (PrE) lineages coincident with implantation of the embryo. The epiblast subsequently undergoes considerable expansion of cell numbers prior to gastrulation. To investigate underlying regulatory principles, we perform...

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Vydáno v:Cell Rep
Hlavní autoři: Mohammed, Hisham, Hernando-Herraez, Irene, Savino, Aurora, Scialdone, Antonio, Macaulay, Iain, Mulas, Carla, Chandra, Tamir, Voet, Thierry, Dean, Wendy, Nichols, Jennifer, Marioni, John C., Reik, Wolf
Médium: Artigo
Jazyk:Inglês
Vydáno: Cell Press 2017
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5554778/
https://ncbi.nlm.nih.gov/pubmed/28768204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2017.07.009
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