Single-Cell Landscape of Transcriptional Heterogeneity and Cell Fate Decisions during Mouse Early Gastrulation

The mouse inner cell mass (ICM) segregates into the epiblast and primitive endoderm (PrE) lineages coincident with implantation of the embryo. The epiblast subsequently undergoes considerable expansion of cell numbers prior to gastrulation. To investigate underlying regulatory principles, we perform...

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Gepubliceerd in:Cell Rep
Hoofdauteurs: Mohammed, Hisham, Hernando-Herraez, Irene, Savino, Aurora, Scialdone, Antonio, Macaulay, Iain, Mulas, Carla, Chandra, Tamir, Voet, Thierry, Dean, Wendy, Nichols, Jennifer, Marioni, John C., Reik, Wolf
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Cell Press 2017
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5554778/
https://ncbi.nlm.nih.gov/pubmed/28768204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2017.07.009
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