Single-Cell Landscape of Transcriptional Heterogeneity and Cell Fate Decisions during Mouse Early Gastrulation

The mouse inner cell mass (ICM) segregates into the epiblast and primitive endoderm (PrE) lineages coincident with implantation of the embryo. The epiblast subsequently undergoes considerable expansion of cell numbers prior to gastrulation. To investigate underlying regulatory principles, we perform...

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Pubblicato in:Cell Rep
Autori principali: Mohammed, Hisham, Hernando-Herraez, Irene, Savino, Aurora, Scialdone, Antonio, Macaulay, Iain, Mulas, Carla, Chandra, Tamir, Voet, Thierry, Dean, Wendy, Nichols, Jennifer, Marioni, John C., Reik, Wolf
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cell Press 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5554778/
https://ncbi.nlm.nih.gov/pubmed/28768204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2017.07.009
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