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Detection of T-cell responses to a ubiquitous cellular protein in autoimmune disease
T cells mediating autoimmune diseases, such as rheumatoid arthritis (RA), are difficult to characterize because they are likely to be deleted or inactivated in the thymus if the self-antigens they recognize are ubiquitously expressed. One way to obtain and analyze these autoimmune T cells is to alte...
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| Veröffentlicht in: | Science |
|---|---|
| Hauptverfasser: | , , , , , , , , , , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5554397/ https://ncbi.nlm.nih.gov/pubmed/25324392 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1259077 |
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