Detection of T-cell responses to a ubiquitous cellular protein in autoimmune disease

T cells mediating autoimmune diseases, such as rheumatoid arthritis (RA), are difficult to characterize because they are likely to be deleted or inactivated in the thymus if the self-antigens they recognize are ubiquitously expressed. One way to obtain and analyze these autoimmune T cells is to alte...

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Publicado no:Science
Main Authors: Ito, Yoshinaga, Hashimoto, Motomu, Hirota, Keiji, Ohkura, Naganari, Morikawa, Hiromasa, Nishikawa, Hiroyoshi, Tanaka, Atsushi, Furu, Moritoshi, Ito, Hiromu, Fujii, Takao, Nomura, Takashi, Yamazaki, Sayuri, Morita, Akimichi, Vignali, Dario A. A., Kappler, John W., Matsuda, Shuichi, Mimori, Tsuneyo, Sakaguchi, Noriko, Sakaguchi, Shimon
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5554397/
https://ncbi.nlm.nih.gov/pubmed/25324392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1259077
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