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Cleavage of the human respiratory syncytial virus fusion protein at two distinct sites is required for activation of membrane fusion

Preparations of purified full-length fusion (F) protein of human respiratory syncytial virus (HRSV) expressed in recombinant vaccinia-F infected cells, or of an anchorless mutant (F(TM(−))) lacking the C-terminal 50 amino acids secreted from vaccinia-F(TM(−))-infected cells contain a minor polypepti...

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Bibliografiske detaljer
Main Authors: González-Reyes, Luis, Ruiz-Argüello, M. Begoña, García-Barreno, Blanca, Calder, Leslie, López, Juan A., Albar, Juan P., Skehel, John J., Wiley, Don C., Melero, José A.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2001
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC55543/
https://ncbi.nlm.nih.gov/pubmed/11493675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.151098198
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