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Recombinant Sendai Viruses Expressing Fusion Proteins with Two Furin Cleavage Sites Mimic the Syncytial and Receptor-Independent Infection Properties of Respiratory Syncytial Virus

Cell entry by paramyxoviruses requires fusion between viral and cellular membranes. Paramyxovirus infection also gives rise to the formation of multinuclear, fused cells (syncytia). Both types of fusion are mediated by the viral fusion (F) protein, which requires proteolytic processing at a basic cl...

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Bibliografiset tiedot
Päätekijät: Rawling, Joanna, Cano, Olga, Garcin, Dominique, Kolakofsky, Daniel, Melero, José A.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Microbiology (ASM) 2011
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3067931/
https://ncbi.nlm.nih.gov/pubmed/21228237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02065-10
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