Regulation of tumour related genes by dynamic epigenetic alteration at enhancer regions in gastric epithelial cells infected by Epstein-Barr virus

Epstein-Barr virus (EBV) infection is associated with tumours such as Burkitt lymphoma, nasopharyngeal carcinoma, and gastric cancer. We previously showed that EBV(+) gastric cancer presents an extremely high-methylation epigenotype and this aberrant DNA methylation causes silencing of multiple tumo...

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Udgivet i:Sci Rep
Main Authors: Okabe, Atsushi, Funata, Sayaka, Matsusaka, Keisuke, Namba, Hiroe, Fukuyo, Masaki, Rahmutulla, Bahityar, Oshima, Motohiko, Iwama, Atsushi, Fukayama, Masashi, Kaneda, Atsushi
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5554293/
https://ncbi.nlm.nih.gov/pubmed/28801683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-08370-7
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