Enhancing NK cell-mediated cytotoxicity to cisplatin-resistant lung cancer cells via MEK/Erk signaling inhibition

Major progress has been made clinically in inhibiting the programmed death receptor 1 (PD-1)/PD-L1 interaction to enhance T cell-mediated immune function, yet the effectiveness of anti-PD-L1/PD-1 agents in enhancing natural killer (NK) cell’s function remains largely unknown. Susceptibilities of cis...

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Bibliographic Details
Published in:Sci Rep
Main Authors: Yang, Li, Shen, MingJing, Xu, Li Jun, Yang, Xiaodong, Tsai, Ying, Keng, Peter C., Chen, Yuhchyau, Lee, Soo Ok
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2017
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5554231/
https://ncbi.nlm.nih.gov/pubmed/28801607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-08483-z
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