Hepatitis C virus replication is directly inhibited by IFN-α in a full-length binary expression system

Hepatitis C virus (HCV) is a leading cause of chronic hepatitis, cirrhosis, and hepatocellular carcinoma. The absence of culture systems permissive for HCV replication has presented a major bottleneck to antiviral development. We sought to recapitulate the early steps in the life cycle of HCV by mea...

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Detalhes bibliográficos
Main Authors: Chung, Raymond T., He, Wenping, Saquib, Afroz, Contreras, Ana M., Xavier, Ramnik J., Chawla, Ashish, Wang, Timothy C., Schmidt, Emmett V.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2001
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC55541/
https://ncbi.nlm.nih.gov/pubmed/11493707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.171319698
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