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Cacna1g is a genetic modifier of epilepsy in a mouse model of Dravet syndrome

Dravet syndrome, an early onset epileptic encephalopathy, is most often caused by de novo mutation of the neuronal voltage-gated sodium channel gene SCN1A. Mouse models with deletion of Scn1a recapitulate Dravet syndrome phenotypes, including spontaneous generalized tonic-clonic seizures, susceptibi...

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Bibliografiske detaljer
Udgivet i:Epilepsia
Main Authors: Calhoun, Jeffrey D., Hawkins, Nicole A., Zachwieja, Nicole J., Kearney, Jennifer A.
Format: Artigo
Sprog:Inglês
Udgivet: 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5554089/
https://ncbi.nlm.nih.gov/pubmed/28556246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/epi.13811
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