The anti-vascular endothelial growth factor receptor-1 monoclonal antibody D16F7 inhibits invasiveness of human glioblastoma and glioblastoma stem cells

BACKGROUND: Glioblastoma (GBM) is a highly migratory, invasive, and angiogenic brain tumor. Like vascular endothelial growth factor-A (VEGF-A), placental growth factor (PlGF) promotes GBM angiogenesis. VEGF-A is a ligand for both VEGF receptor-1 (VEGFR-1) and VEGFR-2, while PlGF interacts exclusivel...

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Bibliografske podrobnosti
izdano v:J Exp Clin Cancer Res
Main Authors: Atzori, Maria Grazia, Tentori, Lucio, Ruffini, Federica, Ceci, Claudia, Lisi, Lucia, Bonanno, Elena, Scimeca, Manuel, Eskilsson, Eskil, Daubon, Thomas, Miletic, Hrvoje, Ricci Vitiani, Lucia, Pallini, Roberto, Navarra, Pierluigi, Bjerkvig, Rolf, D’Atri, Stefania, Lacal, Pedro Miguel, Graziani, Grazia
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2017
Teme:
Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5553938/
https://ncbi.nlm.nih.gov/pubmed/28797294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-017-0577-2
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