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Correlation between endogenous nucleosomal hyper(ADP-ribosyl)ation of histone H1 and the induction of chromatin relaxation.

The effect of poly(ADP-ribose) synthesis on chromatin structure was investigated by velocity sedimentation and electron microscopy. We demonstrate that locally relaxed regions can be generated within polynucleosome chains by the activity of their intrinsic poly(ADP-ribose)polymerase. This relaxation...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Aubin, R J, Fréchette, A, de Murcia, G, Mandel, P, Lord, A, Grondin, G, Poirier, G G
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1983
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC555344/
https://ncbi.nlm.nih.gov/pubmed/6641701
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