Poly(ADP-ribosyl)ation-dependent Transient Chromatin Decondensation and Histone Displacement following Laser Microirradiation

Chromatin undergoes a rapid ATP-dependent, ATM and H2AX-independent decondensation when DNA damage is introduced by laser microirradiation. Although the detailed mechanism of this decondensation remains to be determined, the kinetics of decondensation are similar to the kinetics of poly(ADP-ribosyl)...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Strickfaden, Hilmar, McDonald, Darin, Kruhlak, Michael J., Haince, Jean-Francois, Th'ng, John P. H., Rouleau, Michele, Ishibashi, Toytaka, Corry, Gareth N., Ausio, Juan, Underhill, D. Alan, Poirier, Guy G., Hendzel, Michael J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2016
Assuntos:
DNA and Chromosomes
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4722458/
https://ncbi.nlm.nih.gov/pubmed/26559976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.694992
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