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Monte Carlo simulations of randomized clinical trials in epilepsy

BACKGROUND: The placebo response in epilepsy randomized clinical trials (RCTs) has recently been shown to largely reflect underlying natural variability in seizure frequency. Based on this observation, we sought to explore the parameter space of RCT design to optimize trial efficiency and cost. METH...

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Dades bibliogràfiques
Publicat a:Ann Clin Transl Neurol
Autors principals: Goldenholz, Daniel M., Tharayil, Joseph, Moss, Robert, Myers, Evan, Theodore, William H.
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5553226/
https://ncbi.nlm.nih.gov/pubmed/28812044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/acn3.426
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