Structural Mimicry of the Dengue Virus Envelope Glycoprotein Revealed by the Crystallographic Study of an Idiotype–Anti-idiotype Fab Complex

A detailed understanding of the fine specificity of serotype-specific human antibodies is vital for the development and evaluation of new vaccines for pathogenic flaviviruses such as dengue virus (DENV) and Zika virus. In this study, we thoroughly characterize the structural footprint of an anti-idi...

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Библиографические подробности
Опубликовано в: :J Virol
Главные авторы: Wong, Yee Hwa, Goh, Boon Chong, Lim, She Yah, Teo, En Wei, Lim, Angeline P. C., Dedon, Pete C., Hanson, Brendon J., MacAry, Paul A., Lescar, Julien
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2017
Предметы:
Vaccines and Antiviral Agents
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5553163/
https://ncbi.nlm.nih.gov/pubmed/28637753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00406-17
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