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Structural Mimicry of the Dengue Virus Envelope Glycoprotein Revealed by the Crystallographic Study of an Idiotype–Anti-idiotype Fab Complex

A detailed understanding of the fine specificity of serotype-specific human antibodies is vital for the development and evaluation of new vaccines for pathogenic flaviviruses such as dengue virus (DENV) and Zika virus. In this study, we thoroughly characterize the structural footprint of an anti-idi...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Wong, Yee Hwa, Goh, Boon Chong, Lim, She Yah, Teo, En Wei, Lim, Angeline P. C., Dedon, Pete C., Hanson, Brendon J., MacAry, Paul A., Lescar, Julien
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5553163/
https://ncbi.nlm.nih.gov/pubmed/28637753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00406-17
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