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Soluble epoxide hydrolase inhibition Promotes White Matter Integrity and Long-Term Functional Recovery after chronic hypoperfusion in mice

Chronic cerebral hypoperfusion induced cerebrovascular white matter lesions (WMLs) are closely associated with cognitive impairment and other neurological deficits. The mechanism of demyelination in response to hypoperfusion has not yet been fully clarified. Soluble epoxide hydrolase (sEH) is an end...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Chen, Yuxue, Tian, Hao, Yao, Ensheng, Tian, Yeye, Zhang, Huaqiu, Xu, Li, Yu, Zhiyuan, Fang, Yongkang, Wang, Wei, Du, Peng, Xie, Minjie
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5552839/
https://ncbi.nlm.nih.gov/pubmed/28798352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-08227-z
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