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Soluble Epoxide Hydrolase Dimerization Is Required for Hydrolase Activity
Soluble epoxide hydrolase (sEH) plays a key role in the metabolic conversion of the protective eicosanoid 14,15-epoxyeicosatrienoic acid to 14,15-dihydroxyeicosatrienoic acid. Accordingly, inhibition of sEH hydrolase activity has been shown to be beneficial in multiple models of cardiovascular disea...
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| Main Authors: | , , , , |
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| Formáid: | Artigo |
| Teanga: | Inglês |
| Foilsithe: |
American Society for Biochemistry and Molecular Biology
2013
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| Ábhair: | |
| Rochtain Ar Líne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3597810/ https://ncbi.nlm.nih.gov/pubmed/23362272 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.429258 |
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