Anesthesia and Surgery Impair Blood–Brain Barrier and Cognitive Function in Mice

Blood–brain barrier (BBB) dysfunction, e.g., increase in BBB permeability, has been reported to contribute to cognitive impairment. However, the effects of anesthesia and surgery on BBB permeability, the underlying mechanisms, and associated cognitive function remain largely to be determined. Here,...

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Dettagli Bibliografici
Pubblicato in:Front Immunol
Autori principali: Yang, Siming, Gu, Changping, Mandeville, Emiri T., Dong, Yuanlin, Esposito, Elga, Zhang, Yiying, Yang, Guang, Shen, Yuan, Fu, Xiaobing, Lo, Eng H., Xie, Zhongcong
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2017
Soggetti:
Immunology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5552714/
https://ncbi.nlm.nih.gov/pubmed/28848542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.00902
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