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Rottlerin protected dopaminergic cell line from cytotoxicity of 6-hydroxydopamine by inhibiting PKCδ phosphorylation

OBJECTIVE: The present study aims to investigate the role of protein kinase C δ subtype (PKCδ) phosphorylation in the process of 6-hydroxydopamine (6-OHDA)-induced dopaminergic cell death, and demonstrate the molecular basis of neurological disorders, such as Parkinson’s disease. METHODS: The pheoch...

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Publicado en:Neurosci Bull
Autores principales: Fan, Ying, Zhang, Yan-Qiao, Sun, Dian-Jun, Zhang, Yi-Na, Wu, Xiao-Wei, Li, Jing
Formato: Artigo
Lenguaje:Inglês
Publicado: Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences 2009
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5552553/
https://ncbi.nlm.nih.gov/pubmed/19633700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12264-009-0416-3
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