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Minocycline attenuates cognitive impairment and restrains oxidative stress in the hippocampus of rats with chronic cerebral hypoperfusion

OBJECTIVE: Nitric oxide (NO) was speculated to play an important role in the pathophysiology of cerebral ischemia. Minocycline, a tetracycline derivative, reduced inflammation and protected against cerebral ischemia. To study the neuroprotection mechanism of minocycline for vascular dementia, the in...

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Detalhes bibliográficos
Publicado no:Neurosci Bull
Main Authors: Cai, Zhi-You, Yan, Yong, Sun, Shan-Quan, Zhang, Jun, HUANG, Liang-Guo, Yan, Ning, Wu, Fang, Li, Jie-Ying
Formato: Artigo
Idioma:Inglês
Publicado em: Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5552530/
https://ncbi.nlm.nih.gov/pubmed/18839024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12264-008-0324-y
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