Early treatment of minocycline alleviates white matter and cognitive impairments after chronic cerebral hypoperfusion

Subcortical ischemic vascular dementia (SIVD) caused by chronic cerebral hypoperfusion develops with progressive white matter and cognitive impairments, yet no effective therapy is available. We investigated the temporal effects of minocycline on an experimental SIVD exerted by right unilateral comm...

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Udgivet i:Sci Rep
Main Authors: Ma, Jing, Zhang, Jing, Hou, Wei Wei, Wu, Xiao Hua, Liao, Ru Jia, Chen, Ying, Wang, Zhe, Zhang, Xiang Nan, Zhang, Li San, Zhou, Yu Dong, Chen, Zhong, Hu, Wei Wei
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4502604/
https://ncbi.nlm.nih.gov/pubmed/26174710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep12079
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