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Differentiating the Cochran-Armitage trend test and Pearson’s χ(2) test: location and dispersion

In genetic case-control association studies, a standard practice is to perform the Cochran-Armitage (CA) trend test with 1 degree-of-freedom (df) under the assumption of an additive model. However, when the true genetic model is recessive or near recessive, it is outperformed by Pearson’s χ(2) test...

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Detalhes bibliográficos
Publicado no:Ann Hum Genet
Main Authors: ZHOU, ZHENGYANG, KU, HUNG-CHIH, HUANG, ZHIPENG, XING, GUAN, XING, CHAO
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5552445/
https://ncbi.nlm.nih.gov/pubmed/28653322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/ahg.12202
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