Direct antioxidant properties of methotrexate: Inhibition of malondialdehyde-acetaldehyde-protein adduct formation and superoxide scavenging

Methotrexate (MTX) is an immunosuppressant commonly used for the treatment of autoimmune diseases. Recent observations have shown that patients treated with MTX also exhibit a reduced risk for the development of cardiovascular disease (CVD). Although MTX reduces systemic inflammation and tissue dama...

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Detalles Bibliográficos
Publicado en:Redox Biol
Main Authors: Zimmerman, Matthew C., Clemens, Dahn L., Duryee, Michael J., Sarmiento, Cleofes, Chiou, Andrew, Hunter, Carlos D., Tian, Jun, Klassen, Lynell W., O’Dell, James R., Thiele, Geoffrey M., Mikuls, Ted R., Anderson, Daniel R.
Formato: Artigo
Idioma:Inglês
Publicado: Elsevier 2017
Assuntos:
Research Paper
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5552384/
https://ncbi.nlm.nih.gov/pubmed/28803127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2017.07.018
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