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The tetraspanin CD9 facilitates MERS-coronavirus entry by scaffolding host cell receptors and proteases
Infection by enveloped coronaviruses (CoVs) initiates with viral spike (S) proteins binding to cellular receptors, and is followed by proteolytic cleavage of receptor-bound S proteins, which prompts S protein-mediated virus-cell membrane fusion. Infection therefore requires close proximity of recept...
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| Pubblicato in: | PLoS Pathog |
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| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Public Library of Science
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5552337/ https://ncbi.nlm.nih.gov/pubmed/28759649 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006546 |
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