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The tetraspanin CD9 facilitates MERS-coronavirus entry by scaffolding host cell receptors and proteases

Infection by enveloped coronaviruses (CoVs) initiates with viral spike (S) proteins binding to cellular receptors, and is followed by proteolytic cleavage of receptor-bound S proteins, which prompts S protein-mediated virus-cell membrane fusion. Infection therefore requires close proximity of recept...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Earnest, James T., Hantak, Michael P., Li, Kun, McCray, Paul B., Perlman, Stanley, Gallagher, Tom
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5552337/
https://ncbi.nlm.nih.gov/pubmed/28759649
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006546
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