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The tetraspanin CD9 facilitates MERS-coronavirus entry by scaffolding host cell receptors and proteases
Infection by enveloped coronaviruses (CoVs) initiates with viral spike (S) proteins binding to cellular receptors, and is followed by proteolytic cleavage of receptor-bound S proteins, which prompts S protein-mediated virus-cell membrane fusion. Infection therefore requires close proximity of recept...
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Publicado no: | PLoS Pathog |
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Main Authors: | , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Public Library of Science
2017
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5552337/ https://ncbi.nlm.nih.gov/pubmed/28759649 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006546 |
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