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Coronavirus and Influenza Virus Proteolytic Priming Takes Place in Tetraspanin-Enriched Membrane Microdomains

Coronaviruses (CoVs) and low-pathogenicity influenza A viruses (LP IAVs) depend on target cell proteases to cleave their viral glycoproteins and prime them for virus-cell membrane fusion. Several proteases cluster into tetraspanin-enriched microdomains (TEMs), suggesting that TEMs are preferred viru...

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Bibliografiska uppgifter
I publikationen:J Virol
Huvudupphovsmän: Earnest, James T., Hantak, Michael P., Park, Jung-Eun, Gallagher, Tom
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2015
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4442435/
https://ncbi.nlm.nih.gov/pubmed/25833045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00543-15
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