Rare HIV-1 transmitted/founder lineages identified by deep viral sequencing contribute to rapid shifts in dominant quasispecies during acute and early infection

In order to inform the rational design of HIV-1 preventive and cure interventions it is critical to understand the events occurring during acute HIV-1 infection (AHI). Using viral deep sequencing on six participants from the early capture acute infection RV217 cohort, we have studied HIV-1 evolution...

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出版年:PLoS Pathog
主要な著者: Kijak, Gustavo H., Sanders-Buell, Eric, Chenine, Agnes-Laurence, Eller, Michael A., Goonetilleke, Nilu, Thomas, Rasmi, Leviyang, Sivan, Harbolick, Elizabeth A., Bose, Meera, Pham, Phuc, Oropeza, Celina, Poltavee, Kultida, O’Sullivan, Anne Marie, Billings, Erik, Merbah, Melanie, Costanzo, Margaret C., Warren, Joanna A., Slike, Bonnie, Li, Hui, Peachman, Kristina K., Fischer, Will, Gao, Feng, Cicala, Claudia, Arthos, James, Eller, Leigh A., O’Connell, Robert J., Sinei, Samuel, Maganga, Lucas, Kibuuka, Hannah, Nitayaphan, Sorachai, Rao, Mangala, Marovich, Mary A., Krebs, Shelly J., Rolland, Morgane, Korber, Bette T., Shaw, George M., Michael, Nelson L., Robb, Merlin L., Tovanabutra, Sodsai, Kim, Jerome H.
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2017
主題:
Research Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5552316/
https://ncbi.nlm.nih.gov/pubmed/28759651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006510
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