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Orion: Detecting regions of the human non-coding genome that are intolerant to variation using population genetics
There is broad agreement that genetic mutations occurring outside of the protein-coding regions play a key role in human disease. Despite this consensus, we are not yet capable of discerning which portions of non-coding sequence are important in the context of human disease. Here, we present Orion,...
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| Vydáno v: | PLoS One |
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| Hlavní autoři: | , , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Public Library of Science
2017
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5552289/ https://ncbi.nlm.nih.gov/pubmed/28797091 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0181604 |
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