The Tim-3-galectin-9 Secretory Pathway is Involved in the Immune Escape of Human Acute Myeloid Leukemia Cells

Acute myeloid leukemia (AML) is a severe and often fatal systemic malignancy. Malignant cells are capable of escaping host immune surveillance by inactivating cytotoxic lymphoid cells. In this work we discovered a fundamental molecular pathway, which includes ligand-dependent activation of ectopical...

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Udgivet i:EBioMedicine
Main Authors: Gonçalves Silva, Isabel, Yasinska, Inna M., Sakhnevych, Svetlana S., Fiedler, Walter, Wellbrock, Jasmin, Bardelli, Marco, Varani, Luca, Hussain, Rohanah, Siligardi, Giuliano, Ceccone, Giacomo, Berger, Steffen M., Ushkaryov, Yuri A., Gibbs, Bernhard F., Fasler-Kan, Elizaveta, Sumbayev, Vadim V.
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2017
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5552242/
https://ncbi.nlm.nih.gov/pubmed/28750861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2017.07.018
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