Studies of the antitumor mechanism of action of dermaseptin B2, a multifunctional cationic antimicrobial peptide, reveal a partial implication of cell surface glycosaminoglycans

Dermaseptin-B2 (DRS-B2) is a multifunctional cationic antimicrobial peptide (CAP) isolated from frog skin secretion. We previously reported that DRS-B2 possesses anticancer and antiangiogenic activities in vitro and in vivo. In the present study, we evaluated the antiproliferative activity of DRS-B2...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Dos Santos, Célia, Hamadat, Sabah, Le Saux, Karen, Newton, Clara, Mazouni, Meriem, Zargarian, Loussiné, Miro-Padovani, Mickael, Zadigue, Patricia, Delbé, Jean, Hamma-Kourbali, Yamina, Amiche, Mohamed
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5552233/
https://ncbi.nlm.nih.gov/pubmed/28797092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0182926
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