A Multistage Subunit Vaccine Effectively Protects Mice Against Primary Progressive Tuberculosis, Latency and Reactivation

Adult tuberculosis (TB) is the main cause of TB epidemic and death. The infection results mainly by endogenous reactivation of latent TB infection and secondarily transmitted by exogenous infection. There is no vaccine for adult TB. To this end, we first chose antigens from a potential antigenic res...

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Udgivet i:EBioMedicine
Main Authors: Ma, Jilei, Teng, Xindong, Wang, Xiaochun, Fan, Xionglin, Wu, Yaqi, Tian, Maopeng, Zhou, Zijie, Li, Longmeng
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2017
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5552207/
https://ncbi.nlm.nih.gov/pubmed/28711483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2017.07.005
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