Stabilization of the c-Myc protein by CAMKIIγ promotes T cell lymphoma

Although high c-Myc protein expression is observed alongside MYC amplification in some cancers, in most cases protein overexpression occurs in the absence of gene amplification, e.g. T cell lymphoma (TCL). Here, Ca(2+)/calmodulin-dependent protein kinase II γ (CAMKIIγ) was shown to stabilize the c-M...

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Publicado no:Cancer Cell
Main Authors: Gu, Ying, Zhang, Jiawei, Ma, Xiaoxiao, Kim, Byung-wook, Wang, Hailong, Li, Jinfan, Pan, Yi, Xu, Yang, Ding, Lili, Yang, Lu, Guo, Chao, Wu, Xiwei, Wu, Jun, Wu, Kirk, Gan, Xiaoxian, Li, Gang, Li, Ling, Forman, Stephen J., Chan, Wing-Chung (John), Xu, Rongzhen, Huang, Wendong
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5552197/
https://ncbi.nlm.nih.gov/pubmed/28697340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccell.2017.06.001
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