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Distinct mechanisms obviate the potentially toxic effects of inverted-repeat Alu elements on cellular RNA metabolism
RNA-binding proteins are shown in two independent studies to mediate distinct and beneficial effects to cells by binding to the extensive double-stranded RNA structures of inverted-repeat Alu elements. One study reports stress-induced export of ADAR1p110 to the cytoplasm where it binds inverted-repe...
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| Опубликовано в: : | Nat Struct Mol Biol |
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| Главные авторы: | , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2017
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5552190/ https://ncbi.nlm.nih.gov/pubmed/28586325 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.3416 |
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