RNA gets in phase

Several neurological disorders are linked to tandem nucleotide repeat expansion in the mutated gene. Jain and Vale (2017. Nature. https://doi.org/10.1038/nature22386) show that, above a pathological threshold repeat number, base pairing interactions drive phase separation of RNA into membrane-less g...

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Bibliografiske detaljer
Udgivet i:J Cell Biol
Main Authors: Saha, Shambaditya, Hyman, Anthony A.
Format: Artigo
Sprog:Inglês
Udgivet: The Rockefeller University Press 2017
Fag:
Commentary
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5551722/
https://ncbi.nlm.nih.gov/pubmed/28667121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201706034
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