Polar positioning of phase-separated liquid compartments in cells regulated by an mRNA competition mechanism

P granules are non-membrane-bound RNA-protein compartments that are involved in germline development in C. elegans. They are liquids that condense at one end of the embryo by localized phase separation, driven by gradients of polarity proteins such as the mRNA-binding protein MEX-5. To probe how pol...

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Detalhes bibliográficos
Publicado no:Cell
Main Authors: Saha, Shambaditya, Weber, Christoph A., Nousch, Marco, Hoege, Carsten, Adame-Arana, Omar, Hein, Marco Y., Osborne-Nishimura, Erin, Mahamid, Julia, Jahnel, Marcus, Jawerth, Louise, Pozniakovski, Andrej, Eckmann, Christian R., Jülicher, Frank, Hyman, Anthony A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5034880/
https://ncbi.nlm.nih.gov/pubmed/27594427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2016.08.006
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