Regulation of RhoA by STAT3 coordinates glial scar formation

Understanding how the transcription factor signal transducer and activator of transcription–3 (STAT3) controls glial scar formation may have important clinical implications. We show that astrocytic STAT3 is associated with greater amounts of secreted MMP2, a crucial protease in scar formation. Moreo...

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Detalhes bibliográficos
Publicado no:J Cell Biol
Main Authors: Renault-Mihara, Francois, Mukaino, Masahiko, Shinozaki, Munehisa, Kumamaru, Hiromi, Kawase, Satoshi, Baudoux, Matthieu, Ishibashi, Toshiki, Kawabata, Soya, Nishiyama, Yuichiro, Sugai, Keiko, Yasutake, Kaori, Okada, Seiji, Nakamura, Masaya, Okano, Hideyuki
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2017
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5551705/
https://ncbi.nlm.nih.gov/pubmed/28642362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201610102
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