RAMP2 Influences Glucagon Receptor Pharmacology via Trafficking and Signaling

Endogenous satiety hormones provide an attractive target for obesity drugs. Glucagon causes weight loss by reducing food intake and increasing energy expenditure. To further understand the cellular mechanisms by which glucagon and related ligands activate the glucagon receptor (GCGR), we investigate...

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發表在:Endocrinology
Main Authors: Cegla, Jaimini, Jones, Ben J., Gardiner, James V., Hodson, David J., Marjot, Thomas, McGlone, Emma R., Tan, Tricia M., Bloom, Stephen R.
格式: Artigo
語言:Inglês
出版: Endocrine Society 2017
主題:
Research Articles
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5551549/
https://ncbi.nlm.nih.gov/pubmed/28586439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2016-1755
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