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RAMP2 Influences Glucagon Receptor Pharmacology via Trafficking and Signaling

Endogenous satiety hormones provide an attractive target for obesity drugs. Glucagon causes weight loss by reducing food intake and increasing energy expenditure. To further understand the cellular mechanisms by which glucagon and related ligands activate the glucagon receptor (GCGR), we investigate...

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Detalhes bibliográficos
Publicado no:Endocrinology
Main Authors: Cegla, Jaimini, Jones, Ben J., Gardiner, James V., Hodson, David J., Marjot, Thomas, McGlone, Emma R., Tan, Tricia M., Bloom, Stephen R.
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5551549/
https://ncbi.nlm.nih.gov/pubmed/28586439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2016-1755
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