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RAMP2 Influences Glucagon Receptor Pharmacology via Trafficking and Signaling

Endogenous satiety hormones provide an attractive target for obesity drugs. Glucagon causes weight loss by reducing food intake and increasing energy expenditure. To further understand the cellular mechanisms by which glucagon and related ligands activate the glucagon receptor (GCGR), we investigate...

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Pubblicato in:Endocrinology
Autori principali: Cegla, Jaimini, Jones, Ben J., Gardiner, James V., Hodson, David J., Marjot, Thomas, McGlone, Emma R., Tan, Tricia M., Bloom, Stephen R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Endocrine Society 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5551549/
https://ncbi.nlm.nih.gov/pubmed/28586439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2016-1755
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