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RAMP2 Influences Glucagon Receptor Pharmacology via Trafficking and Signaling

Endogenous satiety hormones provide an attractive target for obesity drugs. Glucagon causes weight loss by reducing food intake and increasing energy expenditure. To further understand the cellular mechanisms by which glucagon and related ligands activate the glucagon receptor (GCGR), we investigate...

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Publicado en:Endocrinology
Main Authors: Cegla, Jaimini, Jones, Ben J., Gardiner, James V., Hodson, David J., Marjot, Thomas, McGlone, Emma R., Tan, Tricia M., Bloom, Stephen R.
Formato: Artigo
Idioma:Inglês
Publicado: Endocrine Society 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5551549/
https://ncbi.nlm.nih.gov/pubmed/28586439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2016-1755
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