Tumor-Infiltrating Lymphocytes and Associations With Pathological Complete Response and Event-Free Survival in HER2-Positive Early-Stage Breast Cancer Treated With Lapatinib and Trastuzumab: A Secondary Analysis of the NeoALTTO Trial

IMPORTANCE: The presence of tumor-infiltrating lymphocytes (TILs) is associated with improved outcomes in human epidermal growth factor receptor 2 (HER2)-positive early breast cancer treated with adjuvant trastuzumab and chemotherapy. The prognostic associations in the neoadjuvant setting of other a...

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Publicado en:JAMA Oncol
Main Authors: Salgado, Roberto, Denkert, Carsten, Campbell, Christine, Savas, Peter, Nuciforo, Paolo, Aura, Claudia, de Azambuja, Evandro, Eidtmann, Holger, Ellis, Catherine E., Baselga, Jose, Piccart-Gebhart, Martine J., Michiels, Stefan, Bradbury, Ian, Sotiriou, Christos, Loi, Sherene
Formato: Artigo
Idioma:Inglês
Publicado: 2015
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5551492/
https://ncbi.nlm.nih.gov/pubmed/26181252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamaoncol.2015.0830
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