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DNA repair dependent NAD+ metabolism is impaired in cells from patients with Fanconi's anemia.

In vitro cultivated fibroblasts derived either from patients with Fanconi's anemia (FA) or from healthy probands were analyzed for their DNA repair-dependent NAD+ metabolism. No difference in NAD+ pools was found. NAD+ consumption after cell damage by u.v. irradiation was, however, significantl...

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Bibliografische gegevens
Hoofdauteurs: Klocker, H, Auer, B, Hirsch-Kauffmann, M, Altmann, H, Burtscher, H J, Schweiger, M
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 1983
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC555133/
https://ncbi.nlm.nih.gov/pubmed/11894942
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